Wednesday, July 11, 2018

Katharine's Appetite Improves with Less Phenobarbital

Today Katharine ate on her own all day long. And she has eaten nothing but AD in a bowl. And she demanded food every hour. By 3 p.m. she had had 115 calories. We weighed her last night and she's at 10.4, up one ounce from 7/3. So,no weight loss which is good. And maybe she only needs about 165 calories a day. She hasn't eaten since 3 and may need hand feeding a bit or maybe she'll eat again on her own. But titrating down the pheno seems to help her eat.

We had her pheno compounded but I think the vet got the script wrong. I'll call the pharmacist tomorrow first. We want to titrate down one dose and make the evening dose a regular 7.5mg dose. She receives a total of 15mg a day. The script compounded says 7.5mg/1ml-7.5mg is in one ML of concentration. That means one dose is 1ml which is a lot to syringe up and try to give her. That also means the TOTAL for the day is 2ml. If it were 15mg/1ml then I could easily give .5ml per dose and titrate down as needed. I need to use a syringe with hundredths measurements which I have but which is hard to read accurately and we are aiming for accuracy. We need to give the exact dose each time so that we can see how it affects her appetite as well as monitor for efficacy for seizure control. This should be more accurate than trying to cut pills that are not scored and that shatter easily.

However, the really confusing part is the script label says to give .9ml per dose. That would only be 13mg total instead of 15mg (.9+.9=1.80ml instead of 2ml.) That would really decrease her pheno which might be dangerous.

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